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MHC class II up-regulation and co-localization with Fas in experimental models of immune-mediated bone marrow failure

OBJECTIVE: To test the hypothesis that gamma interferon (IFN-γ) promotes MHC class II expression on bone marrow (BM) cell targets that facilitates T cell-mediated BM destruction in immune-mediated BM failure. MATERIALS AND METHODS: Allogeneic lymph node (LN) cells were infused into MHC or minor hist...

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Main Authors: Erie, Andrew J., Samsel, Leigh, Takaku, Tomoiku, Desierto, Marie J., Keyvanfar, Keyvan, McCoy, J. Philip, Young, Neal S., Chen, Jichun
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144292/
https://ncbi.nlm.nih.gov/pubmed/21635935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2011.05.005
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