Enrichment of hematopoietic stem cells with SLAM and LSK markers for the detection of hematopoietic stem cell function in normal and Trp53 null mice

OBJECTIVE: To test function of hematopoietic stem cells (HSCs) in vivo in C57BL/6 (B6) and Trp53-deficient (Trp53 null) mice by using two HSC enrichment schemes. METHODS: Bone marrow (BM) Lin(-)CD41(-)CD48(-)CD150(+) (SLAM, signaling lymphocyte activation molecules), Lin(-)CD41(-)CD48(-)CD150(-) (SL...

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Main Authors: Chen, Jichun, Ellison, Felicia M., Keyvanfar, Keyvan, Omokaro, Stephanie O., Desierto, Marie J., Eckhaus, Michael A., Young, Neal S.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583137/
https://ncbi.nlm.nih.gov/pubmed/18562080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2008.04.012
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