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Long-term adaptation to hypoxia preserves hematopoietic stem cell function

Molecular oxygen sustains aerobic life but it also serves as the substrate for oxidative stress that has been associated with the pathogenesis of disease and with aging. Compared to mice housed in normoxia (21% O(2)), reducing ambient oxygen to 10% O(2) (hypoxia) resulted in increased hematopoietic...

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Detalhes bibliográficos
Publicado no:Exp Hematol
Main Authors: Chen, Jichun, Kang, Ju-Gyeong, Keyvanfar, Keyvan, Young, Neal S., Hwang, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506184/
https://ncbi.nlm.nih.gov/pubmed/27118043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2016.04.010
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