Targeting of XJB-5-131 to mitochondria suppresses oxidative DNA damage and motor decline in a mouse model of Huntington’s disease

Oxidative damage and mitochondrial dysfunction are implicated in aging and age-related neurodegenerative diseases, including Huntington’s disease (HD). Many naturally occurring antioxidants have been tested to correct for deleterious effects of reactive oxygen species, but often they lack specificit...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Xun, Zhiyin, Rivera-Sanchez, Sulay, Ayala-Penã, Sylvette, Lim, James, Budworth, Helen, Skoda, Erin M., Robbins, Paul D., Niedernhofer, Laura J., Wipf, Peter, McMurray, Cynthia T.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513647/
https://ncbi.nlm.nih.gov/pubmed/23122961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.10.001
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים