Distinct Pools of Non-Glycolytic Substrates Differentiate Brain Regions and Prime Region-Specific Responses of Mitochondria

Many hereditary diseases are characterized by region-specific toxicity, despite the fact that disease-linked proteins are generally ubiquitously expressed. The underlying basis of the region-specific vulnerability remains enigmatic. Here, we evaluate the fundamental features of mitochondrial and glu...

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Main Authors: Lee, Do Yup, Xun, Zhiyin, Platt, Virginia, Budworth, Helen, Canaria, Christie A., McMurray, Cynthia T.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714274/
https://ncbi.nlm.nih.gov/pubmed/23874783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068831
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