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Retinoic acid-induced differentiation increases the rate of oxygen consumption and enhances the spare respiratory capacity of mitochondria in SH-SY5Y cells

Retinoic acid (RA) is used in differentiation therapy to treat a variety of cancers including neuroblastoma. The contributing factors for its therapeutic efficacy are poorly understood. However, mitochondria (MT) have been implicated as key effectors in RA-mediated differentiation process. Here we u...

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Detalhes bibliográficos
Main Authors: Xun, Zhiyin, Lee, Do-Yup, Lim, James, Canaria, Christie A., Barnebey, Adam, Yanonne, Steven M., McMurray, Cynthia T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357086/
https://ncbi.nlm.nih.gov/pubmed/22336883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2012.01.008
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