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Towards Understanding Region-Specificity of Triplet Repeat Diseases: Coupled Immunohistology and Mass Spectrometry Imaging
Many trinucleotide repeat disorders exhibit region-specific toxicity within tissues, the basis of which cannot be explained by traditional methods. For example, in HD, the toxic disease-causing protein is ubiquitously expressed. However, only the medium spiny neurons in the striatum are initially ta...
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| Publicado en: | Methods Mol Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7191641/ https://ncbi.nlm.nih.gov/pubmed/23754228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-411-1_14 |
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