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CTLA-4 co-receptor impacts on the function of Treg and CD8(+) T-cell subsets
CTLA-4 has potent regulatory effects on the threshold of T-cell signalling and, in the process, guards against the development of hyper-proliferation and autoimmunity. Despite this, the role of CTLA-4 on specific T-cell subsets has been unclear. Such studies could shed light on both the function of...
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| Hlavní autor: | |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3512132/ https://ncbi.nlm.nih.gov/pubmed/19283722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939261 |
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