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CTLA-4 is Required by CD4(+)CD25(+) Treg to Control CD4(+) T Cell Lymphopenia-Induced Proliferation
CTLA-4 is constitutively expressed by CD4+CD25+Foxp3+ regulatory T cells (Treg) but its precise role in Treg function is not clear. Although blockade of CTLA-4 interferes with Treg function, studies using CTLA-4 deficient Treg have failed to reveal an essential requirement for CTLA-4 in Treg suppres...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2835300/ https://ncbi.nlm.nih.gov/pubmed/19462377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838603 |
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