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CTLA-4 co-receptor impacts on the function of Treg and CD8(+) T-cell subsets

CTLA-4 has potent regulatory effects on the threshold of T-cell signalling and, in the process, guards against the development of hyper-proliferation and autoimmunity. Despite this, the role of CTLA-4 on specific T-cell subsets has been unclear. Such studies could shed light on both the function of...

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Bibliografski detalji
Glavni autor: Rudd, Christopher E.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512132/
https://ncbi.nlm.nih.gov/pubmed/19283722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939261
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