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Dynamic force sensing of filamin revealed in single-molecule experiments

Mechanical forces are important signals for cell response and development, but detailed molecular mechanisms of force sensing are largely unexplored. The cytoskeletal protein filamin is a key connecting element between the cytoskeleton and transmembrane complexes such as integrins or the von Willebr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rognoni, Lorenz, Stigler, Johannes, Pelz, Benjamin, Ylänne, Jari, Rief, Matthias
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511698/
https://ncbi.nlm.nih.gov/pubmed/23150587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211274109
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