Lipopolysaccharide-Induced Expression of Microsomal Prostaglandin E Synthase-1 Mediates Late-Phase PGE(2) Production in Bone Marrow Derived Macrophages

Cyclooxygenase (COX)-2 expression and release of prostaglandins (PGs) by macrophages are consistent features of lipopolysaccharide (LPS)-induced macrophage inflammation. The two major PGs, PGE(2) and PGD(2), are synthesized by the prostanoid isomerases, PGE synthases (PGES) and PGD synthases (PGDS),...

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Detalhes bibliográficos
Main Authors: Xiao, Lei, Ornatowska, Magdalena, Zhao, Guiqing, Cao, Hongmei, Yu, Rui, Deng, Jing, Li, Yongchao, Zhao, Qiong, Sadikot, Ruxana T., Christman, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511480/
https://ncbi.nlm.nih.gov/pubmed/23226252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050244
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