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Microsomal prostaglandin E synthase-1: the inducible synthase for prostaglandin E(2)

Microsomal prostaglandin E synthase-1 (mPGES-1) is an inducible enzyme that catalyzes the conversion of prostaglandin (PG)H(2 )to PGE(2). Proinflammatory stimuli markedly increase levels of mPGES-1 expression both in vivo and in vitro. mPGES-1 knockout studies and animal models of inflammatory arthr...

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Autors principals: Sampey, Annaleise V, Monrad, Seetha, Crofford, Leslie J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1174970/
https://ncbi.nlm.nih.gov/pubmed/15899061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1748
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