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Sulforaphane Inhibits Prostaglandin E2 Synthesis by Suppressing Microsomal Prostaglandin E Synthase 1

Sulforaphane (SFN) is a dietary cancer preventive with incompletely characterized mechanism(s) of cancer prevention. Since prostaglandin E2 (PGE2) promotes cancer progression, we hypothesized that SFN may block PGE2 synthesis in cancer cells. We found that SFN indeed blocked PGE2 production in human...

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Detalhes bibliográficos
Main Authors: Zhou, Jiping, Joplin, Denise G., Cross, Janet V., Templeton, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500324/
https://ncbi.nlm.nih.gov/pubmed/23166763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049744
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