Genetic Deletion of Microsomal Prostaglandin E Synthase-1 Suppresses Mouse Mammary Tumor Growth and Angiogenesis

The cyclooxygenase/prostaglandin (COX/PG) signaling pathway is of central importance in inflammation and neoplasia. COX inhibitors are widely used for analgesia and also have demonstrated activity for cancer prophylaxis. However, cardiovascular toxicity associated with this drug class diminishes the...

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Main Authors: Howe, Louise R., Subbaramaiah, Kotha, Kent, Claire V., Zhou, Xi K., Chang, Sung-Hee, Hla, Timothy, Jakobsson, Per-Johan, Hudis, Clifford A., Dannenberg, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830707/
https://ncbi.nlm.nih.gov/pubmed/23624019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2013.04.002
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