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Shunting of prostanoid biosynthesis in microsomal prostaglandin E synthase-1 null embryo fibroblasts: regulatory effects on inducible nitric oxide synthase expression and nitrite synthesis
Microsomal postaglandin (PG) E synthase (mPGES)-1 is an inducible enzyme that acts downstream of cyclooxygenase (COX) and specifically catalyzes the conversion of prostaglandin (PG)H(2) to PGE(2), most prominently in inflammatory conditions. Specific inhibitors of mPGES-1 are not yet available, howe...
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| Gepubliceerd in: | FASEB J |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2006
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4415996/ https://ncbi.nlm.nih.gov/pubmed/17023389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.06-6366fje |
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