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Shunting of prostanoid biosynthesis in microsomal prostaglandin E synthase-1 null embryo fibroblasts: regulatory effects on inducible nitric oxide synthase expression and nitrite synthesis

Microsomal postaglandin (PG) E synthase (mPGES)-1 is an inducible enzyme that acts downstream of cyclooxygenase (COX) and specifically catalyzes the conversion of prostaglandin (PG)H(2) to PGE(2), most prominently in inflammatory conditions. Specific inhibitors of mPGES-1 are not yet available, howe...

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Bibliografiska uppgifter
I publikationen:FASEB J
Huvudupphovsmän: Kapoor, Mohit, Kojima, Fumiaki, Qian, Min, Yang, Lihua, Crofford, Leslie J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415996/
https://ncbi.nlm.nih.gov/pubmed/17023389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.06-6366fje
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