Pivotal Role of Reactive Oxygen Species in Differential Regulation of Lipopolysaccharide-Induced Prostaglandins Production in Macrophages

Gram-negative bacterial endotoxin lipopolysaccharide (LPS) triggers the production of inflammatory cytokines, reactive oxygen species (ROS), and prostaglandins (PGs) by pulmonary macrophages. Here, we investigated if ROS influenced PGs production in response to LPS treatment in mouse bone marrow-der...

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Main Authors: Zhao, Guiqing, Yu, Rui, Deng, Jing, Zhao, Qiong, Li, Yongchao, Joo, Myungsoo, van Breemen, Richard B., Christman, John W., Xiao, Lei
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2013
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533474/
https://ncbi.nlm.nih.gov/pubmed/23071105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.080762
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