Competitive Enzymatic Interactions Determine the Relative Amounts of Prostaglandins E(2) and D(2)

Prostaglandins (PGs) are a family of cellular messengers exerting diverse homeostatic and pathophysiologic effects. Recently, several studies reported significant increases of PGI(2) and PGF(2α) after the inhibition of microsomal PGE synthase-1 (mPGES-1) expression, which indicated that PGH(2) metab...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yu, Rui, Xiao, Lei, Zhao, Guiqing, Christman, John W., van Breemen, Richard B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2011
Schlagworte:
Inflammation, Immunopharmacology, and Asthma
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199988/
https://ncbi.nlm.nih.gov/pubmed/21865441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.185405
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