An improved LC-MS-MS method for the quantification of prostaglandins E(2) and D(2) production in biological fluids

We report an improved LC-MS-MS assay that accurately measures prostaglandins D(2) (PGD(2)) and E(2) (PGE(2)) in cell culture supernatants and other biological fluids. The limit of detection for each prostaglandin was 20 pg/mL (0.20 pg; 0.55 fmol on-column), and the inter-day and intra-day coefficien...

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Bibliografski detalji
Glavni autori: Cao, Hongmei, Xiao, Lei, Park, GyeYoung, Wang, Xuerong, Azim, Anser C., Christman, John W., van Breemen, Richard B.
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276632/
https://ncbi.nlm.nih.gov/pubmed/17976507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2007.08.041
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