Lipopolysaccharide-dependent interaction between PU.1 and cJun determines production of lipocalin-type prostaglandin D synthase and prostaglandin D2 in macrophages

Previously, we reported that expression of lipocalin-prostaglandin D synthase (L-PGDS) is inducible in macrophages and protects from Pseudomonas pneumonia. Here, we investigated the mechanism by which L-PGDS gene expression is induced in macrophages. A promoter analysis of the murine L-PGDS promoter...

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Detalhes bibliográficos
Main Authors: Joo, Myungsoo, Kwon, Minjae, Cho, Yong-Jig, Hu, Ningning, Pedchenko, Tetyana V., Sadikot, Ruxana T., Blackwell, Timothy S., Christman, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681347/
https://ncbi.nlm.nih.gov/pubmed/19181746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90320.2008
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