Hepatitis C Virus Core Protein Suppresses NF-κB Activation and Cyclooxygenase-2 Expression by Direct Interaction with IκB Kinase β

In addition to hepatocytes, hepatitis C virus (HCV) infects immune cells, including macrophages. However, little is known concerning the impact of HCV infection on cellular functions of these immune effector cells. Lipopolysaccharide (LPS) activates IκB kinase (IKK) signalsome and NF-κB, which leads...

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Detalhes bibliográficos
Main Authors: Joo, Myungsoo, Hahn, Young S., Kwon, Minjae, Sadikot, Ruxana T., Blackwell, Timothy S., Christman, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143634/
https://ncbi.nlm.nih.gov/pubmed/15919917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.12.7648-7657.2005
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