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Genetic determination of the role of PU.1 in macrophage gene expression

PU.1, an Ets family transcription factor, mediates macrophage effector function in inflammation by regulating gene expression. But, the extent and nature of PU.1 function in gene expression has not been genetically determined because ablation of PU.1 gene abolishes macrophage development. Here, we e...

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Detalhes bibliográficos
Main Authors: Joo, Myungsoo, Kwon, Minjae, Azim, Anser C., Sadikot, Ruxana T., Blackwell, Timothy S., Christman, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494535/
https://ncbi.nlm.nih.gov/pubmed/18485892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.04.189
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