Nrf2 is essential for the expression of lipocalin–prostaglandin D synthase induced by prostaglandin D(2)

Nrf2 is a transcription factor that protects against inflammatory diseases, but the underlying mechanism of this effect remains unclear. Here, we report that Nrf2 uses lipocalin–prostaglandin D synthase (L-PGDS) as a mechanism for suppressing inflammation. Exogenously added prostaglandin D(2) (PGD(2...

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Bibliografiske detaljer
Main Authors: Kim, Kyun Ha, Sadikot, Ruxana T., Xiao, Lei, Christman, John W., Freeman, Michael L., Chan, Jefferson Y., Oh, Yu-Kyoung, Blackwell, Timothy S., Joo, Myungsoo
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972891/
https://ncbi.nlm.nih.gov/pubmed/24029383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.08.192
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