Identification of PPARgamma Partial Agonists of Natural Origin (I): Development of a Virtual Screening Procedure and In Vitro Validation

BACKGROUND: Although there are successful examples of the discovery of new PPARγ agonists, it has recently been of great interest to identify new PPARγ partial agonists that do not present the adverse side effects caused by PPARγ full agonists. Consequently, the goal of this work was to design, appl...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Guasch, Laura, Sala, Esther, Castell-Auví, Anna, Cedó, Lidia, Liedl, Klaus R., Wolber, Gerhard, Muehlbacher, Markus, Mulero, Miquel, Pinent, Montserrat, Ardévol, Anna, Valls, Cristina, Pujadas, Gerard, Garcia-Vallvé, Santiago
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2012
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511273/
https://ncbi.nlm.nih.gov/pubmed/23226391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050816
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