Identification of Novel Human Dipeptidyl Peptidase-IV Inhibitors of Natural Origin (Part II): In Silico Prediction in Antidiabetic Extracts

BACKGROUND: Natural extracts play an important role in traditional medicines for the treatment of diabetes mellitus and are also an essential resource for new drug discovery. Dipeptidyl peptidase IV (DPP-IV) inhibitors are potential candidates for the treatment of type 2 diabetes mellitus, and the e...

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Main Authors: Guasch, Laura, Sala, Esther, Ojeda, María José, Valls, Cristina, Bladé, Cinta, Mulero, Miquel, Blay, Mayte, Ardévol, Anna, Garcia-Vallvé, Santiago, Pujadas, Gerard
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448616/
https://ncbi.nlm.nih.gov/pubmed/23028712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044972
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