Identification of PPARgamma Partial Agonists of Natural Origin (I): Development of a Virtual Screening Procedure and In Vitro Validation

BACKGROUND: Although there are successful examples of the discovery of new PPARγ agonists, it has recently been of great interest to identify new PPARγ partial agonists that do not present the adverse side effects caused by PPARγ full agonists. Consequently, the goal of this work was to design, appl...

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Bibliografiset tiedot
Päätekijät: Guasch, Laura, Sala, Esther, Castell-Auví, Anna, Cedó, Lidia, Liedl, Klaus R., Wolber, Gerhard, Muehlbacher, Markus, Mulero, Miquel, Pinent, Montserrat, Ardévol, Anna, Valls, Cristina, Pujadas, Gerard, Garcia-Vallvé, Santiago
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2012
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511273/
https://ncbi.nlm.nih.gov/pubmed/23226391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050816
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