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Effects of 6-Thioguanine and S(6)-Methylthioguanine on Transcription in Vitro and in Human Cells
Thiopurine drugs are extensively used as chemotherapeutic agents in clinical practice, even though there is concern about the risk of therapy-related cancers. It has been previously suggested that the cytotoxicity of thiopurine drugs involves their metabolic activation, the resultant generation of 6...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510796/ https://ncbi.nlm.nih.gov/pubmed/23076150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.418681 |
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