تحميل...
LC-MS/MS Coupled with Stable Isotope Dilution Method for the Quantification of 6-Thioguanine and S(6)-Methylthioguanine in Genomic DNA of Human Cancer Cells Treated with 6-Thioguanine
Thiopurines, including mercaptopurine (MP), 6-thioguanine ((S)G) and azathioprine, are widely used for the treatment of many human diseases including acute lymphoblastic leukemia (ALL). To exert their cytotoxic effect, these prodrugs need to be metabolically activated to (S)G nucleotides and incorpo...
محفوظ في:
| المؤلفون الرئيسيون: | , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
2010
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922690/ https://ncbi.nlm.nih.gov/pubmed/20550170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac1008628 |
| الوسوم: |
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