Species-Specific Inhibition of RIG-I Ubiquitination and IFN Induction by the Influenza A Virus NS1 Protein

Influenza A viruses can adapt to new host species, leading to the emergence of novel pathogenic strains. There is evidence that highly pathogenic viruses encode for non-structural 1 (NS1) proteins that are more efficient in suppressing the host immune response. The NS1 protein inhibits type-I interf...

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Bibliographic Details
Main Authors: Rajsbaum, Ricardo, Albrecht, Randy A., Wang, May K., Maharaj, Natalya P., Versteeg, Gijs A., Nistal-Villán, Estanislao, García-Sastre, Adolfo, Gack, Michaela U.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510253/
https://ncbi.nlm.nih.gov/pubmed/23209422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003059
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