CELF4 Regulates Translation and Local Abundance of a Vast Set of mRNAs, Including Genes Associated with Regulation of Synaptic Function

RNA–binding proteins have emerged as causal agents of complex neurological diseases. Mice deficient for neuronal RNA–binding protein CELF4 have a complex neurological disorder with epilepsy as a prominent feature. Human CELF4 has recently been associated with clinical features similar to those seen...

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Main Authors: Wagnon, Jacy L., Briese, Michael, Sun, Wenzhi, Mahaffey, Connie L., Curk, Tomaž, Rot, Gregor, Ule, Jernej, Frankel, Wayne N.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510034/
https://ncbi.nlm.nih.gov/pubmed/23209433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003067
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