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Etiology of a genetically complex seizure disorder in Celf4 mutant mice

Mice deficient for the gene encoding the RNA-binding protein CELF4 (CUGBP, ELAV-like family member 4) have a complex seizure phenotype that includes both convulsive and non-convulsive seizures, depending upon gene dosage and strain background, modeling genetically complex epilepsy. Invertebrate CELF...

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Bibliographic Details
Main Authors: Wagnon, Jacy L., Mahaffey, Connie L., Sun, Wenzhi, Yang, Yan, Chao, Hsiao-Tuan, Frankel, Wayne N.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190060/
https://ncbi.nlm.nih.gov/pubmed/21745337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2011.00717.x
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