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A targeted mutation in Cacng4 exacerbates spike-wave seizures in stargazer (Cacng2) mice
The voltage-dependent calcium channel γ4 subunit protein, CACNG4, is closely related to the γ2 subunit, CACNG2. Both are expressed primarily in the brain and share 53% amino acid identity. The Cacng2 gene is disrupted in the stargazer mouse, with its distinctive phenotype including ataxia, frequent...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2005
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548574/ https://ncbi.nlm.nih.gov/pubmed/15677329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409527102 |
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