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A targeted mutation in Cacng4 exacerbates spike-wave seizures in stargazer (Cacng2) mice
The voltage-dependent calcium channel γ4 subunit protein, CACNG4, is closely related to the γ2 subunit, CACNG2. Both are expressed primarily in the brain and share 53% amino acid identity. The Cacng2 gene is disrupted in the stargazer mouse, with its distinctive phenotype including ataxia, frequent...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548574/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15677329/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409527102 |
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