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Szt2, a novel gene for seizure threshold in mice

In a chemical mutagenesis screen we identified Szt2 (seizure threshold 2) as a gene that confers low seizure threshold to mice and may also enhance epileptogenesis. The semidominant phenotype was mapped to Chromosome 4 and narrowed further to a critical interval of approximately 650 kb. A novel larg...

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Autores principales: Frankel, Wayne N., Yang, Yan, Mahaffey, Connie L., Beyer, Barbara J., O’Brien, Timothy P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728062/
https://ncbi.nlm.nih.gov/pubmed/19624305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2009.00509.x
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