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APOE genotype affects the presynaptic compartment of glutamatergic nerve terminals

Apolipoprotein E (APOE) genotype affects outcomes of Alzheimer’s Disease and other conditions of brain damage. Using APOE knock-in mice, we have previously shown that APOE- ε4 Targeted Replacement (TR) mice have fewer dendritic spines and reduced branching in cortical neurons. Since dendritic spines...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dumanis, Sonya B., DiBattista, Amanda M., Miessau, Matthew, Moussa, Charbel E.H., Rebeck, G. William
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509249/
https://ncbi.nlm.nih.gov/pubmed/22862561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07908.x
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