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Alzheimer’s Disease Genetic Risk Factor APOE-ε4 Also Affects Normal Brain Function

APOE-ε4 is the strongest genetic risk factor for Alzheimer’s disease (AD), and is associated with an increase in the levels of amyloid deposition and an early age of onset. Recent data demonstrate that AD pathological changes occur decades before clinical symptoms, raising questions about the precis...

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Bibliographic Details
Published in:Curr Alzheimer Res
Main Authors: DiBattista, Amanda M., Heinsinger, Nicolette M., Rebeck, G. William
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839141/
https://ncbi.nlm.nih.gov/pubmed/27033053
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