Identification and modification of amyloid-independent phenotypes of APOE4 mice

BACKGROUND: Over 70 million Americans inherit the strongest genetic risk factor for Alzheimer’s disease (AD), apolipoprotein E4 (APOE4), but have no course for reducing their risk. The association of non-steroidal anti-inflammatory drug (NSAID) use with reduced risk of AD for APOE4-carriers suggests...

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Bibliographic Details
Published in:Exp Neurol
Main Authors: DiBattista, Amanda M., Dumanis, Sonya B., Newman, Joshua, Rebeck, G. William
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860139/
https://ncbi.nlm.nih.gov/pubmed/27085394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.04.014
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