Impact of Histone H4 Lysine 20 Methylation on 53BP1 Responses to Chromosomal Double Strand Breaks

Recruitment of 53BP1 to chromatin flanking double strand breaks (DSBs) requires γH2AX/MDC1/RNF8-dependent ubiquitination of chromatin and interaction of 53BP1 with histone H4 methylated on lysine 20 (H4K20me). Several histone methyltransferases have been implicated in 53BP1 recruitment, but their qu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hartlerode, Andrea J., Guan, Yinghua, Rajendran, Anbazhagan, Ura, Kiyoe, Schotta, Gunnar, Xie, Anyong, Shah, Jagesh V., Scully, Ralph
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509127/
https://ncbi.nlm.nih.gov/pubmed/23209566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049211
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