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RELATCH: relative optimality in metabolic networks explains robust metabolic and regulatory responses to perturbations
Predicting cellular responses to perturbations is an important task in systems biology. We report a new approach, RELATCH, which uses flux and gene expression data from a reference state to predict metabolic responses in a genetically or environmentally perturbed state. Using the concept of relative...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2012
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3506949/ https://ncbi.nlm.nih.gov/pubmed/23013597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-9-r78 |
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