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Perturbations in Histidine Biosynthesis Uncover Robustness in the Metabolic Network of Salmonella enterica

Phosphoribosylamine (PRA) is an intermediate in the biosynthetic pathway that is common to thiamine and purines. Glutamine phosphoribosyl pyrophosphate (PRPP) amidotransferase is the product of the purF gene in Salmonella enterica and catalyzes the synthesis of PRA from PRPP and glutamine. Strains l...

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Detalhes bibliográficos
Main Authors: Koenigsknecht, Mark J., Lambrecht, Jennifer A., Fenlon, Luke A., Downs, Diana M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485032/
https://ncbi.nlm.nih.gov/pubmed/23133571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048207
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