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Perturbations in Histidine Biosynthesis Uncover Robustness in the Metabolic Network of Salmonella enterica

Phosphoribosylamine (PRA) is an intermediate in the biosynthetic pathway that is common to thiamine and purines. Glutamine phosphoribosyl pyrophosphate (PRPP) amidotransferase is the product of the purF gene in Salmonella enterica and catalyzes the synthesis of PRA from PRPP and glutamine. Strains l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Koenigsknecht, Mark J., Lambrecht, Jennifer A., Fenlon, Luke A., Downs, Diana M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485032/
https://ncbi.nlm.nih.gov/pubmed/23133571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048207
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