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Analysis of ThiC Variants in the Context of the Metabolic Network of Salmonella enterica

In bacteria, the 4-amino-hydroxymethyl-2-methylpyrimidine (HMP) moiety of thiamine is synthesized from 5-aminoimidazole ribotide (AIR), a branch point metabolite of purine and thiamine biosynthesis. ThiC is a member of the radical S-adenosylmethionine (AdoMet) superfamily and catalyzes the complex c...

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Autors principals: Palmer, Lauren D., Dougherty, Michael J., Downs, Diana M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486400/
https://ncbi.nlm.nih.gov/pubmed/22961850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01361-12
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