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An Automated Phenotype-Driven Approach (GeneForce) for Refining Metabolic and Regulatory Models
Integrated constraint-based metabolic and regulatory models can accurately predict cellular growth phenotypes arising from genetic and environmental perturbations. Challenges in constructing such models involve the limited availability of information about transcription factor—gene target interactio...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965739/ https://ncbi.nlm.nih.gov/pubmed/21060853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000970 |
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