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An Automated Phenotype-Driven Approach (GeneForce) for Refining Metabolic and Regulatory Models

Integrated constraint-based metabolic and regulatory models can accurately predict cellular growth phenotypes arising from genetic and environmental perturbations. Challenges in constructing such models involve the limited availability of information about transcription factor—gene target interactio...

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Hlavní autoři: Barua, Dipak, Kim, Joonhoon, Reed, Jennifer L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965739/
https://ncbi.nlm.nih.gov/pubmed/21060853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000970
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