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Large-Scale Bi-Level Strain Design Approaches and Mixed-Integer Programming Solution Techniques

The use of computational models in metabolic engineering has been increasing as more genome-scale metabolic models and computational approaches become available. Various computational approaches have been developed to predict how genetic perturbations affect metabolic behavior at a systems level, an...

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Detalhes bibliográficos
Main Authors: Kim, Joonhoon, Reed, Jennifer L., Maravelias, Christos T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175644/
https://ncbi.nlm.nih.gov/pubmed/21949695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024162
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