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An Automated Phenotype-Driven Approach (GeneForce) for Refining Metabolic and Regulatory Models
Integrated constraint-based metabolic and regulatory models can accurately predict cellular growth phenotypes arising from genetic and environmental perturbations. Challenges in constructing such models involve the limited availability of information about transcription factor—gene target interactio...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2965739/ https://ncbi.nlm.nih.gov/pubmed/21060853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000970 |
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