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Metabolic Constraint-Based Refinement of Transcriptional Regulatory Networks

There is a strong need for computational frameworks that integrate different biological processes and data-types to unravel cellular regulation. Current efforts to reconstruct transcriptional regulatory networks (TRNs) focus primarily on proximal data such as gene co-expression and transcription fac...

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Autori principali: Chandrasekaran, Sriram, Price, Nathan D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857774/
https://ncbi.nlm.nih.gov/pubmed/24348226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003370
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