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Analysis of optimality in natural and perturbed metabolic networks

An important goal of whole-cell computational modeling is to integrate detailed biochemical information with biological intuition to produce testable predictions. Based on the premise that prokaryotes such as Escherichia coli have maximized their growth performance along evolution, flux balance anal...

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Detalhes bibliográficos
Main Authors: Segrè, Daniel, Vitkup, Dennis, Church, George M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC137552/
https://ncbi.nlm.nih.gov/pubmed/12415116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.232349399
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