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Optimizing bioconversion pathways through systems analysis and metabolic engineering
We demonstrate a general approach for metabolic engineering of biocatalytic systems comprising the uses of a chemostat for strain improvement and radioisotopic tracers for the quantification of pathway fluxes. Flux determination allows the identification of target pathways for modification as valida...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122274/ https://ncbi.nlm.nih.gov/pubmed/11854482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032681699 |
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