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The Role of Molecular Simulations in the Development of Inhibitors of Amyloid β-Peptide Aggregation for the Treatment of Alzheimer’s Disease

[Image: see text] The pathogenic aggregation of the amyloid β-peptide (Aβ) is considered a hallmark of the progression of Alzheimer’s disease, the leading cause of senile dementia in the elderly and one of the principal causes of death in the United States. In the absence of effective therapeutics,...

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Autors principals: Lemkul, Justin A., Bevan, David R.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2012
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503341/
https://ncbi.nlm.nih.gov/pubmed/23173066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300091a
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